Answer:
Explanation:
The switch from glutamic acid to valine in position 6 of hemoglobin (HB) forms the basis of sickle cell anemia disease pathology.
Valine is hydrophobic and it's chain is shorter than glutamic acid. The lack of the carboxylic acid and shortness of valine will result in loss of the ionic interactions formed between the glutamic acid's carboxylic group and other amino acids. A hydrophobic cavity will form in the beta sheet of HB due to the short and hydrophobic structure of valine. For these reasons, the HB molecule will be less stable and insoluble in water. The insolubility is thought to be caused by fibril formation between the valine interacting with hydrophobic pocket residues of the adjacent HB molecule. This would in turn affect binding of oxygen to HB.
Answer:
a population or community.
Explanation:
Answer:
Look at the explanation!
Explanation:
The Mercator map projection is a cylindrical map projection that was presented by Gerardus Mercator in 1569. Gerardus Mercator was a Flemish geographer and cartographer. It became the standard map projection for navigation because of it's cool one of a kind property of "representing any course of constant bearing as a straight segment."
Answer:
Common examples include carbon, sulfur, oxygen, iron, copper, aluminium. Elements are represented by symbols. Compounds are substances made from atoms of different elements joined by chemical bonds. They can only be separated by a chemical reaction.
Explanation:
Substances can be categorised as either elements or compounds. Both of these are made up of atoms, the only difference is an element is made of one type of atom whereas compounds are made of two or more different types of atoms.
Answer:
50%
Explanation:
According to the given information, the woman has normal BRCA alleles while the man carries one copy of the mutated BRCA allele (BRCA1). A diploid organism such as human beings can have two BRCA alleles. A child gets one BRCA allele from the mother and the other from the father.
The child of the couple would get one normal allele from the woman. However, with respect to the BRCA allele, the man would form two types of gametes in equal proportion. The 50% of his gametes would have the mutated BRCA1 allele while the rest 50% would carry the normal BRCA allele. Therefore, the man can transmit either normal or mutated BRCA allele to the child. So, there are 50% chances for the child to get the mutated allele.
