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Mnenie [13.5K]
3 years ago
6

Much of the joint damage characteristics of rhematoid arthritis appears to be caused primarily by secretions of injurious cytoki

nes
Health
1 answer:
aev [14]3 years ago
3 0

Answer:

<em><u>The answer is</u></em>: <u>Cytokines act as mediators responsible for the inflammatory process.</u>

<u />

Explanation:

<u>Rheumatoid arthritis (RA)</u> is a systemic autoimmune disease characterized by synovitis and progressive destruction of the joint cartilage and underlying bone, together with diverse extra-articular manifestations. Cytokines act as soluble effector mediators of the inflammatory process. Therapeutic neutralization with monoclonal antibodies against the pro-inflammatory cytokines TNF-alpha and interleukin 1 (IL-1) has shown a clear efficacy on inflammation and clinical manifestations of RA, although a percentage of patients do not respond.

<em><u>The answer is</u></em>: <u>Cytokines act as mediators responsible for the inflammatory process.</u>

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