Question

Sickle-cell disease is caused by a single mutation in the DNA of a particular gene. A person with this disease has red levels, blood clots, and strokes. This is an example of___________________.
A. codominance.
B. a multifactorial trait.
C. pleiotropy.
D. incomplete dominance.
E. polygenic inheritance.

Answer 1

Answer:

The correct answer is option C. "pleiotropy".

Explanation:

Pleiotropy is a characteristic that defines a gene that is responsible for the development of multiple traits, which often seem to be unrelated. Sickle-cell disease is an example of a disease caused by the mutation of a pleiotropic gene, resulting in the person developing red levels, blood clots, and strokes. Other example is the disease phenylketonuria, at which the affected person suffers from a mental disorder and reduced hair and skin pigmentation by a single mutation in a single gene on chromosome 12.