Answer: A gyrus (plural = gyri) is the ridge of one of those wrinkles, and a sulcus (plural = sulci) is the groove between two gyri. The pattern of these folds of tissue indicates specific regions of the cerebral cortex. The head is limited by the size of the birth canal, and the brain must fit inside the cranial cavity of the skull.
Explanation: Hope this helps :)
Sickle cell anemia is a genetic condition that distorts the shape of the hemoglobin. This reduces the capacity of the red blood cells to carry oxygen. Another effect is that the distorted red blood cells come together forming a heavy and compact collection of cells that can block the flow of blood. The sedimentation rate is increased by sickle cell anemia.