<h2>KDEL Sequence & Protein Unfolding</h2>
Explanation:
(a) The distinction between proteins sent out from and those held in the ER has all the earmarks of being represented by two unmistakable sorts of focusing on successions that explicitly mark proteins as either bound for transport to the Golgi or bound for maintenance in the ER. Numerous proteins are held in the ER lumen because of the nearness of the focusing on grouping Lys-Asp-Glu-Leu (KDEL, in the single-letter code) at their carboxy end. In the event that this succession is erased from a protein that is regularly held in the ER (e.g., BiP), the transformed protein is rather moved to the Golgi and emitted from the cell. On the other hand, the expansion of the KDEL arrangement to the carboxy end of proteins that are typically discharged makes them be held in the ER. The maintenance of some trans membrane proteins in the ER is comparatively directed by short C-terminal successions that contain two lysine deposits (KKXX sequences)
(b) Proteins are large molecules composed of folded chains of amino acids. Every protein has a unique shape and that shape determines the things it does. You could think of them as keys that fit into certain locks around the body Proteins do lots of different things around the body, including speeding up biological processes, recognizing antibodies, providing structure to certain body parts, transporting substances, regulating genes, and responding to signals inside and outside the body Proteins range in size from small ones, such as insulin - only 51 amino acids long, to extremely large ones, such as titin almost 27,000 amino acids long. No matter their size, they must be folded into a particular shape in order to function. Sometimes, though, things go wrong and cause the protein to unfold
Answer:
Which type of cell can not reproduce by Mitosis?
Blood cells after giving blood
C Nerve cells in the brain
Cells in your digestive tract
Skin cells on the hand
0/1 pts
Explanation:
The main reason why the testes are suspended within the scrotum is to provide cooler temperature for the testes and make it fertile for penetrating the egg. The Scrotum may contract or lengthen depending on the temperature of its surrounding.
- Provide the family with lead education
- Consider treating the child with appropriate chelation therapy
- Refer the child to a clinical center specializing in lead poisoning
If the blood lead level<span> of a preschooler is found to be between 20 and 44 mcg/dL, the nurse should provide lead education to the family. The nurse should also consider treating the child with appropriate chelation therapy. The nurse may refer the child to a clinical center specializing in lead poisoning. The nurse should refer the child to social services if the child’s blood lead level is between 15 and 19 mcg/dL. The nurse should immediately provide diagnostic testing and initiate chelation therapy if the child’s blood lead level is 70 mcg/dL or greater.</span>
