The correct answer to this open question is the following.
Plantation production of sugar and tobacco and the mining of silver in the Americas impacted the economies of Europe, South America, and East Asia due to the trading activities of the so-called Columbian exchange.
During the Columbian exchange, the North American colonies exported to Europe and other regions raw materials and natural resources that were transformed in Europe. Those goods were returned to the Americas and other territories.
As part of this Columbian exchange, Europeans spread many diseases throughout the Americas that almost wipe out 80% of the Native American, Mesoamerican, and South American Indians population. We are talking about diseases such as smallpox, chickenpox, malaria, cholera, and influenza.
