Answer:
The miRNAs act as post-transcriptional silencers, as they are similar to specific mRNAs and regulate their stability and translation. They are small endogenous non-coding ribonucleic acid (RNA) molecules, with about 22 nucleotides, which act as regulators of gene expression in plants and animals, at the post-transcriptional level through the cleavage of a target messenger RNA (mRNA) or repression of translation.
In general, most miRNA genes are transcribed by RNA polymerase II in the nucleus in primary miRNAs (pri-miRNAs). Individually, a pri-miRNA can produce a single miRNA or contain groups of two or more miRNAs that are processed from a common primary transcript. These long pri-miRNA are cleaved by a complex comprising the double-stranded RNAse III enzyme (DROSHA) and its essential cofactor, the binding protein DGCR8 (DiGeorge Syndrome Critical Region 8 protein) in mammals. DROSHA contains two domains of RNAse III, each of which cleaves a strand of the RNA resulting in the precursor microRNA (pre-miRNA) with about 70 base pairs, which contains a double-stranded stretch and a single-stranded loop, forming a structure in clamp. The pre-miRNA is exported to the cytoplasm by the protein exportin-5 (XPO-5), where it is cleaved by DICER1, an RNAse III that assesses the 3 'and 5' ends of the pre-miRNA, generating a mature miRNA with about 22 nucleotides. The processing of pre-miRNA by Dicer promotes the unfolding of the RNA duplex in the form of a clamp. The position in the formation of the clamp can also influence the choice of tape.
Explanation:
Well for the very last sentence it would be if any of the organs shut down it could seriously hurt someone or possibly even kill them if their brain,heart or some other important organ shuts down it could kill them.
There are other minor organs where if it shuts down it wouldn't really hurt the person too much. Sorry I couldn't help you with the other ones though.
Answer:
B
Explanation:
Light shows duality i.e it shows properties of both particle as well as wave.
Answer: Temperature control
Explanation:
Arterio-venous anastomoses (AVAs) are direct connections between small arteries and small veins. In humans they are numerous in the glabrous skin of the hands and feet.
They are very significant in body temperature control. These temperature control are under the dual control of the central nervous system and the local thermal influence. While the arteriovenous anastomoses control the skin temperature through volume changes in the superficial venous bed, the arterioles and capillaries operate by generalized dilatation which results both in increased temperature and in redness of the skin.
