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Rashid [163]
3 years ago
7

MicroRNA (miRNA) production occurs in several steps. Arrange the statements describing the production and function of miRNAs in

the order in which they occur.
Biology
1 answer:
zmey [24]3 years ago
7 0

Answer:

The miRNAs act as post-transcriptional silencers, as they are similar to specific mRNAs and regulate their stability and translation. They are small endogenous non-coding ribonucleic acid (RNA) molecules, with about 22 nucleotides, which act as regulators of gene expression in plants and animals, at the post-transcriptional level through the cleavage of a target messenger RNA (mRNA) or repression of translation.

In general, most miRNA genes are transcribed by RNA polymerase II in the nucleus in primary miRNAs (pri-miRNAs). Individually, a pri-miRNA can produce a single miRNA or contain groups of two or more miRNAs that are processed from a common primary transcript. These long pri-miRNA are cleaved by a complex comprising the double-stranded RNAse III enzyme (DROSHA) and its essential cofactor, the binding protein DGCR8 (DiGeorge Syndrome Critical Region 8 protein) in mammals. DROSHA contains two domains of RNAse III, each of which cleaves a strand of the RNA resulting in the precursor microRNA (pre-miRNA) with about 70 base pairs, which contains a double-stranded stretch and a single-stranded loop, forming a structure in clamp. The pre-miRNA is exported to the cytoplasm by the protein exportin-5 (XPO-5), where it is cleaved by DICER1, an RNAse III that assesses the 3 'and 5' ends of the pre-miRNA, generating a mature miRNA with about 22 nucleotides. The processing of pre-miRNA by Dicer promotes the unfolding of the RNA duplex in the form of a clamp. The position in the formation of the clamp can also influence the choice of tape.

Explanation:

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The front of the white paper packet of the OSL dosimeters
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Answer:

Option a

Explanation:

The front of the white paper packet of the OSL dosimeters may be color-coded to facilitate correct usage and placement of the badge on the body of occupationally exposed personnel.

OSL dosimeters are recently developed and are of high quality than thermoluminescent dosimeters.  It is used to monitor patients health status. Furthermore, it is very sensitive to any change or drop in reading. it give accurate readings even at 1 mrem for both gamma ray photos and X-rays.

Reference: Yukihara, E. G., et al. "Evaluation of optically stimulated luminescence (OSL) dosimeters for passive dosimetry of high‐energy photon and electron beams in radiotherapy." Medical physics 35.1 (2008): 260-269.

7 0
3 years ago
This type of selection means selective breeding of plants and animals
Talja [164]
Artificial Selection.
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5 0
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Name any two organs involved in digestive systemgifjritxudufhg​
patriot [66]

Answer small and large intestines

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3 years ago
What are these species a type of?
GaryK [48]

Answer:

They could all become some sort of food for people.

Explanation: Hope this helps! :)

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3 years ago
Anthony Clement is applying for a car loan. The lending institution requires a personal net worth statement. Anthony currently h
Gelneren [198K]

Answer:

Net worth statement of Anthony

Assets

Current {}                          {}                           $1,085.00

Property, Camera (present value)    {}          $635.00

Total Assets        {}                                        $1,720.00  

Liabilities

Money owed others (Vista Travel)  {}            $305.00

Money owed others (Kelly Electronics)  {}       $83.00

Total Liabilities          {}                                    $388.00

Net Worth                      {}                               $1,332.00

Explanation:

A net worth statement also known as a balance sheet statement is way to present the standing of a business at a particular time. It is a record of the assets and the values of the assets as well as the business liabilities and other outstanding financial obligations the business is to settle.

3 0
3 years ago
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