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Rashid [163]
3 years ago
7

MicroRNA (miRNA) production occurs in several steps. Arrange the statements describing the production and function of miRNAs in

the order in which they occur.
Biology
1 answer:
zmey [24]3 years ago
7 0

Answer:

The miRNAs act as post-transcriptional silencers, as they are similar to specific mRNAs and regulate their stability and translation. They are small endogenous non-coding ribonucleic acid (RNA) molecules, with about 22 nucleotides, which act as regulators of gene expression in plants and animals, at the post-transcriptional level through the cleavage of a target messenger RNA (mRNA) or repression of translation.

In general, most miRNA genes are transcribed by RNA polymerase II in the nucleus in primary miRNAs (pri-miRNAs). Individually, a pri-miRNA can produce a single miRNA or contain groups of two or more miRNAs that are processed from a common primary transcript. These long pri-miRNA are cleaved by a complex comprising the double-stranded RNAse III enzyme (DROSHA) and its essential cofactor, the binding protein DGCR8 (DiGeorge Syndrome Critical Region 8 protein) in mammals. DROSHA contains two domains of RNAse III, each of which cleaves a strand of the RNA resulting in the precursor microRNA (pre-miRNA) with about 70 base pairs, which contains a double-stranded stretch and a single-stranded loop, forming a structure in clamp. The pre-miRNA is exported to the cytoplasm by the protein exportin-5 (XPO-5), where it is cleaved by DICER1, an RNAse III that assesses the 3 'and 5' ends of the pre-miRNA, generating a mature miRNA with about 22 nucleotides. The processing of pre-miRNA by Dicer promotes the unfolding of the RNA duplex in the form of a clamp. The position in the formation of the clamp can also influence the choice of tape.

Explanation:

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mylen [45]

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5 0
3 years ago
During which period did humans first appear on Earth? Quaternary Neogene Paleogene Cenozoic
anyanavicka [17]

The answer is Neogene

Explanation:

It cannot be Cenozoic because that is an era. Not a period. Paleogene, Neogene, and Quaternary (our current period) are all periods within the Cenozoic Era (our current era). On the geologic time scale, there are Eras, Periods, and Epochs (and a few more classifications). Humans first appeared in the Miocene epoch which is an epoch in the Neogene period (in the Cenozoic era).

This is why the answer is Neogene.

Hope this helps...

5 1
3 years ago
Read 2 more answers
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Ostrovityanka [42]
<span>Planaria have a huge regenerative power because of the presence of adult stem cells called neoblasts. If you cut Planaria into pieces, each piece can regenerate into a complete organism and that’s a form of asexual reproduction. Cells which are located on the wound site proliferate to form a blastema-mass of cell that will grow into a new organ. Those cells will differentiate into new tissues and regenerate the missing parts.</span>
<span>The similar thing is happening with starfish.</span>
7 0
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6 0
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