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Drug-drug interactions (DDIs) are one of the commonest causes of medication error in developed countries, particularly in the elderly due to poly-therapy, with a prevalence of 20-40%. In particular, poly-therapy increases the complexity of therapeutic management and thereby the risk of clinically important DDIs, which can both induce the development of adverse drug reactions or reduce the clinical efficacy. DDIs can be classify into two main groups: pharmacokinetic and pharmacodynamic. In this review, using Medline, PubMed, Embase, Cochrane library and Reference lists we searched articles published until June 30 2012, and we described the mechanism of pharmacokinetic DDIs focusing the interest on their clinical implications.
Keywords: Absorption, adverse drug reaction, distribution, drug-drug interactions, excretion, metabolism, poly-therapy
Anemia is a condition in which you lack enough healthy red blood cells to carry adequate oxygen to your body's tissues. Having anemia can make you feel tired and weak. There are many forms of anemia, each with its own cause. Anemia can be temporary or long term, and it can range from mild to severe
Your respiratory system relies on your circulatory system to deliver the oxygen it gathers, while the muscles of your heart cannot function without the oxygen they receive from your lungs. The bones of your skull and spine protect your brain and spinal cord, but your brain regulates the position of your bones by controlling your muscles.
Cya broski
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i believe its alveoli
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