When salt and sugar dissolve in water it is a physical change. The chemical makeup of the salt and sugar are not changed.
Physical change
<span><span>The carboxyl end of the G- protein-coupled receptor (GPCR) is located in the cytosol (it is intracellular). Carboxyl terminus is one of the most variable structures of the protein. All of the GPCR are </span><span>structural and functional similar, unlike their ligands.</span></span>