<span>Within eukaryotic cells, there is a network of organelles which have unique functions.
An organelle is termed as a specialized subunit within a cell which has specific functions and their functions are very vital for a cell to live. Organelles can be identified by microscopy and purified by cell fractionation.
In eukaryotic cells has many types of organelles. Larger organelles which are found in eukaryotic cells are visible with the light microscope, for example, vacuole and nucleus.
Some of the major eukaryotic organelles include plastid, endoplasmic reticulum, flagellum, mitochondrion, vacuole, nucleus and Golgi apparatus</span>
The heart
hope it's fine :P
A biomass pyramid shows the total mass of the organisms that each trophic level occupies in an ecosystem. Usually, producers have a higher biomass than any other trophic level, but there can be lower amounts of biomass at the bottom of the pyramid if the rate of primary production per unit biomass is very fast.
Answer:
Explanation:
Pharmacophore (pharmacology) - The molecular framework responsible for a drug's biological activity. According to IUPAC — A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response.
Privileged structures are defined as molecular frameworks which are able of providing useful ligands for more than one type of receptor or enzyme target by judicious structural modifications.
1) The 1,4-dihydropyridine ring is present in many biologically important molecules that acts as an important scaffold for cardiovascular drug - a calcium antagonists and although it is technically not considered as a pharmacophore, it is considered as a privileged structure.
1,4-Dihydropyridine (DHP), belongs to the class of calcium antagonist that inhibits the influx of extracellular Ca+2 through the L-type voltage-dependent calcium channels.
A positional substitution in the 4-position is feasible in the heterocyclic ring which in turn culminates in various calcium channel antagonist activities and this heterocyclic ring is the common feature for various pharmacological activities such as anti-inflammatory activity, analgesic activity,
antihypertensive, antianginal, antitumor, antitubercular activity and antithrombotic .
Position on the heterocyclic ring binds to the L-type channel and also to N-type channel on membranes.
2.) The bioisosteres are not a suitable bioisostere for the traditional C-4 aryl or heteroaryl substitution which is necessary for calcium ion blockage thereby inhibiting it to function with the mechanism shared above.
I believe the answer is Government subsidies. A subsidy is the form of cash payment or a tax reduction. It is normally given to remove some type of burden, and it is often considered to be in the overall interest of the public, given to promote a social good or economic policy. Tax subsidy; the government can create the same outcome through selective tax breaks as through cash payment. For example, suppose a government sends monetary assistance that reimburses 15% of all health expenditures to a group that is paying 15% income tax. Tax subsidies are also known as tax expenditures.
