Lets eliminate
A. organ transplant:
this was debated maybe 200 years ago (give or tak) and is no longer an issue
B. genetic engineerign
this is kind of debated becuase some scientists are trying to make life and that has to do with ethics because they would be playing god
C. space exploration
not debatable
D. prosthetics
we already have this and tis i not debatable
answer is B
Missouri Compromise is your answer.
They was forced in hard labor