Answer:
"The smallpox vaccine does not contain smallpox virus and cannot spread or cause smallpox. However, the vaccine does contain another virus called vaccinia which is live in the vaccine. Because the virus is alive, it can spread to other parts of the body or to other people from the vaccine site."
[Copy and pasted from a medical website]
Striated muscles contain repeating sarcomeres of overlapping arrays of long, thin actin and thicker myosin filaments. Myosin filaments contains the myosin heads, which are enzymes that can bind to actin, split and make use of the energy from ATP. When muscle contraction starts, myosin heads bind to actin, change their configuration on actin, liberating the products of ATP hydrolysis and causing slide of the actin and myosin filaments. The action of the proteins troponin and tropomyosin on the actin filaments regulates vertebrae striated muscle contraction. The release of calcium ions from the sarcoplasmic reticulum is triggered by the nervous stimulation which causes depolarization of muscle membrane. Calcium ions bind to troponin and thus cause or allow the tropomyosin strands on the actin filament to move so that the part of the actin surface where myosin heads need to bind is uncovered. Contraction then occurs and only stops when the sarcoplasmic reticulum pumps calcium out of the muscle interior.
So basically, what triggers the uncovering of the myosin binding site on actin is the calcium ions binding to troponin and changing configuration.
Answer:
Electric current – The net movement of electric charges in a single direction through a wire or conductor. Voltage difference – The force that causes electric charges to flow; charges flow from high voltage to low voltage
Explanation: