The invasion of the North American continent and its peoples began with the Spanish in 1565 at St. Augustine, Florida, then British in 1587
A. Sumer river was the location along the Tigris and Euphrates Rivers in the land of Mesopotamia.
When European settlers came over to the New World, they brought many diseases with them that the Native Americans had no immunity to. For this reason, they started dying from sicknesses and decrease their numbers by the millions.