A graduated cylinder measures the volume of an object.
Answer:
The plasma membrane is made up by a phospholipid bilayer with embedded proteins that separates the internal contents of the cell from its surrounding environment. Only relatively small, non- polar materials can easily move through the lipid bilayer of the plasma membrane.
Explanation:
Snakes can live up to 9 years. They slither up to 18 mph. Snakes are reptiles that are elongated, limbless, and carnivorous. Another interesting thing about snakes is that they don’t have eyelids. The last fact is that snakes can open there mouths up to 150 degrees so they can swallow there prey.
<span><span>a. amino acid supplements.
</span>Amino acids are polymers that creates the macromolecule of proteins. To explain clearly there are two factors that determine the shape or structure of the proteins which is mainly influenced by the amino acids.
The two factors that determine the shape of a protein </span><span><span>
1. </span> Primary structure. The sequence of amino acids. Amino acids are the building blocks of protein. It is a strong of linearity that can be thousands in length. Moreover, the formation of the amino acid and its system is influenced by its genes’ nucleotides arrangement. </span>
<span>2. Hence the next factor is how is the structure of the amino acids bended and folded with itself that forms the certain protein molecule and forms the larger complex structure</span><span>
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Answer:
TNF-alpha is expressed as a homotrimer that exerts its activities through binding to two types of receptors: TNFR1 and TNFR2, which are transmembrane glycoproteins characterized by having an extracellular domain with 4 cysteine-rich domains (CRD 1-4) , each with 3 cysteinecysteine disulfide bonds.
Explanation:
TNF-alpha (Tumor Necrosis Factor), which has the characteristic of being a paracrine signaling ligand, is a pleiotropic cytokine that functions as a mediator of immune regulation, the inflammatory response and apoptosis in some cell types. Receptors in this family are involved, with some exceptions, in juxtacrine signaling; that is, both the ligand and the receptor are membrane proteins with extracellular domains through which signaling is established. The cellular responses promoted by TNF are initiated by its interaction with two different types of cell receptors, the type I receptor (55 kDa) and the type II receptor (75 kDa). Both types of receptors are part of the TNF receptor family, members of which include Fas antigen (apoptosis inducer, also called Apo-1 or CD95), CD27 (T-cell activation antigen), CD30 (lymphoma marker Hodgkin) and CD40 (B-cell antigen), which share the characteristic of cysteine-rich sequences in their extracellular domains. This family of cytokines generate cellular responses that include differentiation, proliferation, activation of NFκB and cell death, promoting the aggregation of receptor monomers, that is, they have a transmembrane domain that participates in the solubilization of the receptor and a domain of intracellular death that is involved in signal transduction. The binding of TNF to TNF-R1 induces a signaling cascade through its intracellular death domain, which subsequently leads to the activation of complex I (or inflammatory) of NFkB and proceeds to the transcription of anti-apoptotic genes, pro- inflammatory diseases and apoptosis complex II (caspases).
