Lipids differ from carbohydrates the following ways: lipids are not soluble in water and their hydrogen-oxygen ratio is different. Correct answer: B&D. Lipids are diverse group of organic compounds including fats, oils, hormones.. They are also made of hydrogen, oxygen, and carbon like the carbohydrates. However, lipids do not readily combine with water. Some fats are solid (body fat), some are liquid (oils on our skin). The hydrogen-oxygen ratio is also different: In carbohydrates the C:H:O is 1:2:1 (one carbon ,two hydrogen and one oxygen), while in lipids the components are the same but the ratio is less for oxygen, so it is 1:2:less than one for C:H:O.