Air attacks, ground attacks, ground troops
1776-1777 was the turning point in the American Revolutionary War.
The response to apartheid was heavily against it. Numerous European and American countries were together in the opinion that the apartheid was bad and needed to end. This resulted in South Africa isolating itself more and more and eventually it opened up again when apartheid ended.
Spanish missions sought to promote to Native Americans the tenets of agriculture and Catholicism. This was often attempted by forcing Native peoples together to close quarters around the mission. This led to a high death toll as diseases spread rampant from the Spanish to the Native peoples.