B and E, since not everyone believes in supernatural beings or the affects of astrological signs
The answer is in your heart and soul
From tiny blood cells/vessels!
Hope this helps!
Answer;
Insulin and the growth hormone
The hormones that are involved in building and maintaining healthy bone tissues are Insulin and growth hormone
Explanation;
Insulin has some anabolic properties for bone. It is uncertain whether insulin stimulates bone directly or indirectly by increasing muscle work and thus skeletal loading.
Growth hormone is a peptide hormone secreted from the pituitary gland under the control of hypothalamus. It directly and through IGF-I stimulates osteoblast proliferation and activity, promoting bone formation. Additionally it stimulates osteoclast differentiation and activity,promoting bone resorption.
I do not think the industrial and agricultural revolutions could have occurred without the environmental costs. The industrial revolution in the 18th century occurred at a time in history when people where not aware of the consequences of their actions or the consequences of the widespread use of fossil fuels. Even if they were aware the technology would not have been present to harness power from natural renewable sources of energy.