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Zina [86]
3 years ago
11

QUESTION 2

Medicine
1 answer:
Ierofanga [76]3 years ago
5 0
<h3><u>Diabetes mellitus and Diabetes Insipidus </u></h3>

Explanation:

Diabetes mellitus and diabetes insipidus are both metabolic endocrine diseases caused due to hormonal imbalance.

<u>Etiology</u><u>: </u>

<u>Organ and hormone involved</u><u>:  </u>

Diabetes mellitus occurs due to inefficiency of the pancreas to produce sufficient amount of the hormone insulin or lack of insulin action resulting in uncontrolled blood glucose levels.

Diabetes insipidus occurs due to inefficiency of the pituitary glands to produce sufficient amount of the antidiuretic hormone vasopressin or lack of vasopressin action resulting in uncontrolled water metabolism.

<u>Signs and symptoms: </u>

Diabetes mellitus results in increasing blood glucose levels, polyuria and nocturia, polydipsia, polyphagia, fatigue and various other complications affecting eyes, kidneys, nervous system, and heart as the disease progresses.

Diabetes insipidus results in increasing water levels due kidneys excreting large amounts of diluted urine leading to polyuria, polydipsia, and excessive dehydration and fatigue.

<u>Diagnostic/lab tests and results: </u>

Diabetes mellitus is tested by testing blood glucose levels.

Diabetes insipidus is tested by testing water deprivation or vasopressin level test/the 24-hour urine for urine osmolality levels along with serum electrolyte level tests.

These tests are based on response to vasopressin, urine concentration abilities, urine osmolality, and electrolyte levels of the blood.

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Januvia, the trade name for sitagliptin, was introduced in 2006 for the treatment of type 2 diabetes. In what type of orbital do
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In the following orbital the lone pair on each N atom is present:

N1: sp3,

N2: p,

N3: p,

N4: sp2,

N5: sp2

Sitagliptin is an anti-diabetic drug used to treat type 2 diabetes and is marketed under the brand names Januvia and others. One carbon atom has no pi bonds, while the first nitrogen atom is linked to two hydrogen atoms. It thus possesses sp3 hybridization.

The second nitrogen atom possesses a single pair of electrons and is bound to three other atoms. It is hence sp2 hybridized. The nitrogen atoms in positions 3, 4, and 5 have sp2 hybridization.

The lone pair of nitrogen in the first nitrogen atom is in the sp3 orbital. The second and third nitrogen atoms' only pair of electrons are in p-orbitals. The fourth and fifth nitrogen atoms' lone pair of electrons are in sp2 orbitals.

Here is another question with an answer similar to this about Sitagliptin: brainly.com/question/28275161

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