There are three main factors that affect the mutation rates in an organism. The three are:
1. <span>Frequency of Primary Changes in DNA
2. </span><span>Probability of Repair
3. </span><span>Probability of Recognition</span>
Graphs that are clearly labeled are much less likely to be misread or misinterpreted.
Answer:
The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.
Explanation:
Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.
The temperature increases as you go deeper in the aquatic system.
