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Evgesh-ka [11]
3 years ago
8

Rb is an important protein for controlling cell proliferation by blocking entry into S phase. How does it exert its effect?

Biology
1 answer:
amid [387]3 years ago
5 0

Answer:

The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.

Explanation:

Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.

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Explanation: The characteristics that define an organism to be classified as animal are:-

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3 years ago
Imagine meiosis in a diploid organism that only has a single chromosome. Like most diploid organisms, it received one copy of th
Lelechka [254]

Answer:

two of the gametes will Java chromosomes identical to the chromosomes found in the original diploid cell,while two of the gametes will have chromosomes that are different

6 0
3 years ago
Only answer if you know the answer
Volgvan

Answer:

B. A helicase enzyme unwinds the DNA molecule, then corresponding nucleotides are added to the separated original strand forming two separate semiconservative molecules

Explanation:

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2 years ago
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dangina [55]

Answer:

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Explanation:

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Based on this, all the different plants, animals, fungi, microorganisms, and variety of ecosystems found on Earth is the option that best defines biodiversity. The other options leaves out the variety (talked about only one species) and biological aspect of the term.

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3 years ago
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