1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
Evgesh-ka [11]
3 years ago
8

Rb is an important protein for controlling cell proliferation by blocking entry into S phase. How does it exert its effect?

Biology
1 answer:
amid [387]3 years ago
5 0

Answer:

The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.

Explanation:

Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.

You might be interested in
PLEASE ANSWER QUICKLY
Rasek [7]

Answer:

incomplete dominance

Explanation:

This is because incomplete dorminance is a type of inheritance pattern in which a dorminant allele does not completely masked the effect of recessive allele. The recessive allele is expressed little and the dorminant. Example is the nose size. The allele for big nose and recessive allele for small nose are not completely dorminant.

6 0
2 years ago
Raccoons living in cities have learned to open the lids of garbage cans. This
-Dominant- [34]

Answer:I think the first one

Explanation:

8 0
2 years ago
Read 2 more answers
(b) Explain the action of enzymes during a reaction.​
tino4ka555 [31]

Answer:

An enzyme attracts substrates to it's active site, catalyzesthe chemical reaction by which products are formed and then allows the products to Daso create separate from the enzyme surface the combination formula by an enzyme and its abstract is is called the enzyme substrate complex.

5 0
3 years ago
What are the main purposes of a budget check all that apply
andreev551 [17]

The purpose is to help us achieve our life-span goals. And to ensure that our income allocated is being best suited to achieving our life-span we need to review our budget at least once a year. And if you change your goals you should also review the budget so that you achieve the short-term and life-span goals. 

7 0
3 years ago
What processes does not involve the replication of chromosomes
uysha [10]

Answer:

Mitosis

Explanation:

Mitosis does not include replication of chromosomes. If this helped you, Brainliest is appreciated.

4 0
3 years ago
Other questions:
  • How butterflies self-medicate1. de roode notes that animals besides humans self-medicate. from your own knowledge of animals, wh
    10·1 answer
  • Earth lies within the ______ of our solar system
    10·2 answers
  • Tp-13 what is the best course of action if you see a thunderstorm approaching?
    12·2 answers
  • Identify the items that are part of an ecosystem. Check all that apply.
    10·2 answers
  • Eutrophication can cause excess algae growth. Which of the following describes how nutrients contribute to eutrophication?
    8·1 answer
  • Which of the following is not a possible consequence of the introduction of invasive species? a. changes to the existing gene po
    15·2 answers
  • A DNA molecule is a<br> pls answer thx
    10·2 answers
  • The ____is a process often used by scientists to help them solve problems
    9·2 answers
  • What is endocrinegland?​
    10·1 answer
  • In the process of nitrogen fixation,__________ Convert ___________ To forms of nitrogen that plants can use.
    9·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!