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Evgesh-ka [11]
3 years ago
8

Rb is an important protein for controlling cell proliferation by blocking entry into S phase. How does it exert its effect?

Biology
1 answer:
amid [387]3 years ago
5 0

Answer:

The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.

Explanation:

Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.

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The development of the cell theory involved ___________________________.
hammer [34]

The answer is A


The development of the cell theory involved different ideas from different scientist.


To support my answer it was created to Matthias and Theodor,however, there were like many other scientists like Rudolf contributed to the theory.


I hope that's help:0

Please chose me for the Brainliest answer :) thx

6 0
3 years ago
Sickled red blood cells are believed to block blood that is trying to exit the corpus​ spongiosum, which for men​ causes:
Xelga [282]

Answer:

Answer is B. Priapism.

Explanation:

Corpus spongiosum are the three cylinders encased in the bucks fascia. They run through the glass and shaft of the penis, and during erection, they contain almost 85-90% of theology volume.

Priapism can be described as persistent erection of the penis, which is caused by excessive blood flow to the penis or when blood is trapped inside the penis blood chambers I. e, corpus spongiosum.

Priapism can be of two types, they are

1. High- flow Priapism : this is caused when the artery supplying blood to the penis is damaged, thereby, causing it to be oversupplied with oxygenated blood. This type is not painful and can be treated by adopting cold therapy, the use of ice packs.

2. Low-flow Priapism : This occurs when old blood is trapped inside the penis blood chambers. This type is very painful and require urgent medical attention.

Note that, the second type of priapism,low-flow priapism, is caused in the case of a sickled-cell person, because the shape of the blood cell can easily trap blood in the penis.

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3 years ago
What is menstrual cycle? ​
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One is pulmonary one is cellular
3 0
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The process of respiration is essential in the oxygen/carbono dioxide carbon cycle. Respiration remoces From the atmosphere and
irakobra [83]

Answer:

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3 years ago
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