You need to know if the parents trait are dominant or recessive
Answer:
1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).
2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).
Explanation:
In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.
<u>Normal hemoglobin protein in a RBC</u>
DNA CTG ACT CCT GAG GAG AAG TCT
Amino acids Leu Thr Pro Glu Glu Lys Ser
<u>Sickle cell hemoglobin protein in a RBC</u>
DNA CTG ACT CCT <em>GTG</em> GAG AAG TCT
Amino acids Leu Thr Pro <em>Val</em> Glu Lys Ser
When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.
Answer:
Explanation:
Scientific Research is a method used in the construction and testing of a scientific hypothesis.
It has six steps that can be used in solving questions ask or observations made which is A family wants to test the effectiveness of a misting shower head in conserving (saving) water compared to their regular shower head.
Steps to follow:
Make an observation: An observation would be made on how water is been used in the house and how it can be conserved, this observation is what brings about the question asked
Ask a question : The question is
which is more effective in conserving water a misting shower head or regular shower.
Form a hypothesis, or testable explanation: An hypothesis is formulated for the question asked
Example: Null hypothesis: Mistling shower conserves more water than shower head
Alternative: Mistling shower conserves less water that normal shower.
Make a prediction based on the hypothesis: Predictions are made on what could be the cause if there is indeed a difference and what could cause the difference
Test the prediction: An experiment is conducted to test the hypothesis if indeed Mistling is better than normal shower, the appropriate method is determined to be used for the experiment.
Iterate: The result gotten helps to butters our hypothesis if its to be acceoted or rejected. If rejected further research can be conducted on the effectiveness of normal shower in conserving water.
Answer:
Dioecious and monoecious plants actually have something in common, in that they both bear unisexual flowers. This means that each bloom has only male or female reproductive parts. With dioecious plants, the male and female blossoms appear on separate plants. With monoecious plants, each plant has both male and female flowers.
Explanation:
