Answer:
A. It Shows that organisms have changed over time.
Explanation:
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From these observations, the researcher may use bottom up approach to suggest that the blood clotting properties of COX-2 inhibitors lead to heart failure.
Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Blood often backs up and causes fluid to build up in the lungs (congest) and in the legs. The fluid buildup can cause shortness of breath and swelling of the legs and feet. Poor blood flow may cause the skin to appear blue (cyanotic).
Learn more about blood here:
brainly.com/question/14781793
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