Answer:
Thermosensitive liposomes (TSL) are promising tools used to deliver drugs to targeted region when local hyperthermia is applied (∼40–42°C) which triggers the membrane phase transformation from a solid gel-like state to a highly permeable liquid state. Selective lipid components have been used to in TSL formulations to increase plasma stability before hyperthermia and speed drug release rate after. Two generations of TSL technology have been developed. The traditional thermal sensitive liposomes (TTSL) have utilized DPPC and DSPC as a combination. The second generation, lysolipid thermally sensitive liposomes (LTSL) technology, has been developed with incorporation of lysolipids that form stabilized defects at phase transition temperature. LTSL maintains certain favorable attributes:
High percentage of lysolipids incorporation;
Minimum leakage for therapeutical drugs encapsulation;
Ultrafast drug release upon heating (3.5 times enhanced compared to TTSL). For example, ThermoDox, a commonly used LTSL drug for cancer, has been reported to release 100% of the encapsulated doxorubicin within 30s;
First and most successful formulation for intravascular drug release.
Explanation:
https://www.creative-biostructure.com/Lysolipid-Thermally-Sensitive-Liposomes-Production-612.htm
In the cell, the function of the smooth endoplasmic reticulum is that it produce lipids, which are fats and oils. They also transport materials..
Answer:
25% heterozygous tall
Explanation:
If we take the F1 generation as parents and let them self-fertilise, we have 4 crosses.
The first one for homozygous tall, then we have 100% AA.
The second and third one for heterozygous tall and we have 25% AA, 50%Aa and 25%aa for each of them.
The last one would be for dwarf, and we'll have 100%aa.
Adding all of them, we'll have
AA = 100 + 25 + 25 = 150%
Aa = 50+50 = 100%
aa = 100 + 25 + 25 = 150%
as we had 4 crosses, so dividing the total percentages by 4, we'll have,
AA = 37.5%
Aa = 25%
aa = 37.5%
:. The percentage of heterozygous tall would be 25%.
Hope it helps:)
