Question

How are mammalian cells similar and different from yeast? How can they be used to study cancer?

Answer 1

Answer:

Hello, congratulations on your observation! Let me explain.

Yeasts are unicellular eukaryotic organisms. This implies that: they reproduce easily and quickly, they have all the characteristics of a eukaryotic model and their maintenance is really simple and economical (once their cultivation has been developed).

While it is true that they present differences with other eukaryotes, such as patterns of glycation and dependence and / or exclusivity of some substrates, but even if they are a cell model easy to use in the early stages of research, for example in cancer. It allows a first approach of the metabolic and cellular machineries that take place in our cells.  Later in the development of experiments, it may be necessary to use another study model, such as the mouse, rat or pig.