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\if you mean most famous then its the Mona lisa
The factors that contributed to the development of High Renaissance painting were twofold. Traditionally, Italian artists had painted in tempera paint. During the High Renaissance, artists began to use oil paints, which are easier to manipulate and allow the artist to create softer forms .
What i understand from the statement given is that the expression will be:
10m + n/4
where m = 5 and n = 16
now by putting the values of m and n in the expression,we get
10(5) + 16/4
=50 + 4
= 54
Thus, after solving the expression we get the answer 54.