A mutation in the hemoglobin gene cause what disorder?
2 answers:
Answer:
Sickle cell anemia
Explanation:
The mutation is the reversal of an A-T pair in the DNA that replaces a glutamic acid molecule with a valine in the hemoglobin protein.
The changed hemoglobin molecules clump together and cause the red blood cells to change to a crescent or sickle shape that can block blood vessels.
The decreased number of normal red blood cells causes anemia.
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