Answer: equilibrium phenomenon
Explanation:
<span>Lafora disease is the most severe teenage-onset progressive epilepsy, a unique form of glycogenosis with perikaryal accumulation of an abnormal form of glycogen, and a neurodegenerative disorder exhibiting an unusual generalized organellar disintegration. The disease is caused by mutations of the EPM2A gene, which encodes two isoforms of the laforin protein tyrosine phosphatase, having alternate carboxyl termini, one localized in the cytoplasm (endoplasmic reticulum) and the other in the nucleus. To date, all documented disease mutations, including the knockout mouse model deletion, have been in the segment of the protein common to both isoforms. It is therefore not known whether dysfunction of the cytoplasmic, nuclear, or both isoforms leads to the disease. In the present work, we identify six novel mutations, one of which, c.950insT (Q319fs), is the first mutation specific to the cytoplasmic laforin isoform, implicating this isoform in disease pathogenesis. To confirm this mutation's deleterious effect on laforin, we studied the resultant protein's subcellular localization and function and show a drastic reduction in its phosphatase activity, despite maintenance of its location at the endoplasmic reticulum.
I got my information from </span>https://www.ncbi.nlm.nih.gov/pubmed/14722920
<u><em>Female:</em></u>
*Ovaries - release of oocytes (eggs), estrogen and progesterone.
*Oviducts (fallopian tubes) - where fertilization of the oocyte occurs to form a zygote.
*Uterus - where the zygote develops
*Cervix and vagina - allow for the entry of sperm for fertilization
<u><em>Male:</em></u>
*Testes - Releases testosterone and sperm
*Vas deferens - Passageway for sperm
*Epididymis - allows the sperm to pass from the testes and vas deferens and equips them with semen so they can survive internal fertilization
*Penis - releases sperm into the external environment for fertilization to occur
I hope I helped!
D, correct me if i’m wrong
Important factor defining the desert biomes is its tendency to lose water by evaporation, and this potential for water loss exceeds the annual rainfall and defines what organism can live in there.
