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s2008m [1.1K]
3 years ago
10

A number of different types of mutations in the HBB gene can cause human β-thalassemia, a disease characterized by various level

s of anemia. Many of these mutations occur within introns or in upstream noncoding sequences. Explain why mutations in these regions often lead to severe disease, although they may not directly alter the coding regions of the gene.
Biology
1 answer:
Lubov Fominskaja [6]3 years ago
3 0

Answer:

Mutations in introns create alternative splicing site which in turn make mRNA with reduced or no translation.

Explanation:

Introns regulate the splicing of heterogenous RNA during post transcriptional modifications as well as affect the stability of mature mRNA. The stable mRNA is more likely to be translated into proteins. So, introns also regulate the translation of mRNA.  

In human beta thalassemia, mutations in intron create alternative splicing sites which in turn affect the formation of beta globin chain of hemoglobin. Lack of beta globin chain reduces the amount of functional hemoglobin and causes anemia.

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Katen [24]
Answer: i think so ha ha

Explanation: I am not a Human
4 0
3 years ago
A chloroplast has stopped producing atp and NADPH
ElenaW [278]

The question is incomplete, so the complete question is as follows:

A chloroplast has stopped producing ATP and NADPH. Which of the following is most likely causing this?

a.The chloroplast has used up its supply of chlorophyll molecules.

b.Electrons have stopped moving through the electron transport chain.

c.The sun has risen and the chloroplast now can make more chlorophyll.

Answer:

b.Electrons have stopped moving through the electron transport chain.

Explanation:

ATP and NADPH are produced in the light dependent reaction stage of the photosynthesis that occurs within chloroplast grana.

ATP and NADPH are produced due to the movement of electron and proton (H+) in the electron transport chain, so if the movement of electrons will stopped in the electron transport chain, the formation of ATP and NADPH will also get stop.

Hence, the correct answer is "b".

5 0
3 years ago
Describe four human activities that have negative effects on earth's ecosystems. how do human activities increase the occurrence
vova2212 [387]
There are a lot of human activities that gives negative effects on the earth's ecosystem but I will mention only four: Burning of things such as garbages or plants and trees, dumping of garbages anywhere, chemical substance that are being made and produced, cutting down of trees for replacement of buildings and homes. The human activities increase the occurrence of species extinction by doing this, it eliminates and destroy the homes of the species that are supposed to be living on their natural habitat. But instead of them, living peacefully, by doing these activities, their home will be destroyed that can kill them-- which can lead to extinction. 
4 0
3 years ago
Describe and define some aspect of exocytosis or endocytosis?
Sav [38]

Answer:

Exocytosis: It is defined as the process of membrane-bound vesicles fusing with the plasma membrane and later releasing their contents to the extracellular part of the cell.

Endocytosis: It is defined as the process of capturing a particle from outside the cell by the engulfing process with the cell membrane. It is basically two types:

1) Pinocytosis: Cellular drinking.

2) Phagocytosis: Cellular eating.

8 0
3 years ago
NEED HELP QUICK PLEASE HELP
kozerog [31]

Answer:

Question 1

D

Question 2

C

Question 3

D

Explanation:

1. An ecosystem is MOST likely to return to its original condition after Tall prairie grass burns after being struck by lightning.

Here is a research paper in which they explained how this happened. (Komarek, E. V. (1971). Lightning and fire ecology in Africa. In Tall Timbers Fire Ecology Conference (Vol. 11, pp. 473-509).)

2. In some national parks, controlled fires are maintained by firefighters. The major reasons for using controlled burns to maintain certain ecosystems is to give nonnative plants a chance to colonize the region.

A recent article provided the insight of this situation (Xanthopoulos, G., Delogu, G. M., Leone, V., Correia, F. J., & Magalhães, C. G. (2020). Firefighting approaches and extreme wildfires. In Extreme Wildfire Events and Disasters (pp. 117-132). Elsevier.)

3. One reason for the change in the Galápagos ecosystem has been the introduction of species that were not on the island before, such as donkeys, goats, cats, dogs, and insects. The introduction of nonnative species MOST likely disrupt the balance of life on the islands due to greater competition for limited food sources.

Scientist said that food competition is actually a struggle to survive in any ecosystem here is the reference paper (Eckhardt, R. C. (1972). Introduced plants and animals in the Galapagos Islands. Bioscience, 22(10), 585-590.)

5 0
3 years ago
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