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shusha [124]
3 years ago
15

In sickle-cell disease, as a result of a single amino acid change, the hemoglobin tetramers associate with each other and assemb

le into large fibers. Based on this information alone, we can conclude that sickle-cell hemoglobin exhibits ________.
Biology
1 answer:
Phoenix [80]3 years ago
7 0

Answer:

One of the common genetic disorders is sickle cell anemia, in which 2 recessive alleles must meet to allow for destruction and alteration in the morphology of red blood cells. This usually leads to loss of proper binding of oxygen to hemoglobin and curved, sickle-shaped erythrocytes. The mutation causing this disease occurs in the 6th codon of the HBB gene encoding the hemoglobin subunit β (β-globin), a protein, serving as an integral part of the adult hemoglobin A (HbA), which is a heterotetramer of 2 α chains and 2 β chains that is responsible for binding to the oxygen in the blood. This mutation changes a charged glutamic acid to a hydrophobic valine residue and disrupts the tertiary structure and stability of the hemoglobin molecule. Since in the field of protein intrinsic disorder, charged and polar residues are typically considered as disorder promoting, in opposite to the order-promoting non-polar hydrophobic residues, in this study we attempted to answer a question if intrinsic disorder might have a role in the pathogenesis of sickle cell anemia. To this end, several disorder predictors were utilized to evaluate the presence of intrinsically disordered regions in all subunits of human hemoglobin: α, β, δ, ε, ζ, γ1, and γ2. Then, structural analysis was completed by using the SWISS-MODEL Repository to visualize the outputs of the disorder predictors. Finally, Uniprot STRING and D2P2 were used to determine biochemical interactome and protein partners for each hemoglobin subunit along with analyzing their posttranslational modifications. All these properties were used to determine any differences between the 6 different types of subunits of hemoglobin and to correlate the mutation leading to sickle cell anemia with intrinsic disorder propensity.

Explanation:

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4 functions of proteins
Mila [183]

Answer:

Enzyme Activity- Responsible reactions Enzyme catalyze nearby substrates

Cell to Cell Recognition- Recognize molecules on surface of the other cells

Cell Signalling- A chemical messenger that binds a membrane protein causing to change shape and relay the message inside a cell.

Transport materials- Provides channels for a certain solutes to pass through membrane

7 0
2 years ago
What is the probability that a seed from a parent plant of genotype Rr will carry the r gene
daser333 [38]
The answer is 50 percent.

Parent plant of genotype Rr will in meiosis produce haploid gametes which will carry either R allele or r allele. Since there are only two possibilities R or r, the probability that seed will get r gene is 1 of 2. This can be presented as 1/2, which is 50%.
7 0
3 years ago
Read 2 more answers
Which statements accurately describe the roles of decomposers in the carbon cycle?
ollegr [7]

Answer:

The question is incomplete, here's the complete question;

Which statements accurately describe the roles of decomposers in the carbon cycle? Check all that apply.

-Decomposers release carbon dioxide into the air as waste.

-Decomposers remove carbon dioxide from the air during photosynthesis.

-Decomposers break down the remains of dead plants and animals.

-Decomposers return carbon compounds to the soil.

-Decomposers use carbon to make food molecules.

The correct answer is;

Decomposers release carbon dioxide into the air as waste.

Decomposers break down the remains of dead plants and animals.

Decomposers return carbon compounds to the soil.

Explanation:

In the earth, all living things are made up of carbon. Carbon cycle is the process in which carbon travels from the atmosphere into living things in the earth and then returned into the atmosphere.  Carbon is released into the atmosphere through processes like respiration, decomposition, combustion etc. The carbon cycle explains how carbon is stored, made available to living things and replaced on earth. Plants absorb carbon in the form of carbon dioxide from the atmosphere and use it to produce food (glucose) and release oxygen in a process called photosynthesis. When animals feed on these plants , the carbon is transferred to them and thus passes it along the food chain. During respiration, animals release carbon dioxide back into the atmosphere. When the organisms eventually die, the carbon from them is put back into the atmosphere by decomposers so that other living organisms can use it. Decomposers break down dead organisms , releases carbon dioxide through cellular respiration and enriches the soil with nutrients.  The examples of decomposers are bacteria, fungi and worms. Bacteria decomposes most types of organic matter. Fungi are the main decomposers in the forest as they break down wood and the cellulose in plant cell walls. Decomposers are very important because they release carbon locked up in the dead organisms back into the atmosphere and without carbon dioxide in the atmosphere plants can not produce glucose and oxygen.

8 0
3 years ago
Which tasks does a volcanologist do to study volcanoes? Check all that apply.
NeX [460]

A volcanologist is a geologist who studies the process involved in the formation of a volcano. He also studies the eruptive nature of the volcano along with their current and historic eruptions.

The tasks done by a volcanologist do to study volcanoes are =

1. use autoclaves to imitate the interior of a volcano

2. simulate volcanic explosions with computer programs

3. study lava samples

4. listen to the sounds of the interior of a volcano

7 0
3 years ago
Read 2 more answers
All of the following are found in a chloroplast except
Viktor [21]
It seems you forgot your options, but here are some things found in a chloroplast:

grana
Granal thylakoids
Stroma
Nukleloids (DNA rings)
Ribosomes
Starch granules
membranes

Now, some examples of thing NOT found in a chloroplast:

Endoplasmic Reticulum (that's another organelle)
7 0
3 years ago
Read 2 more answers
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