I guess it would be everything that they know is now what we know
The main way in which European motivations for exploration changed after the discovery of the Americas is that after the discovery many European nations became obsessed with colonization and extracting as many resources from the New World as possible.
Answer: The westward expansion resulted in Native Americans move to another place that they did not like.
Explanation: Native Americans was eventually forced to live on designated reservations. The expansion also had a affect on the bison (Buffalo). They would kill them so they would move out of the way of the trains