A genetic disorder in which the deformation of red blood cells occurs due to which transportation of oxygen is hindered is called sickle cell anemia.
Further Explanation:
The inherited form of anemia is sickle cell anemia. <u>It is a condition during which the body contains an inadequate amount of red blood cells to fulfill the required supply of oxygen in the body. </u>The normal red blood cells are round and flexible and move with ease through the blood vessels. <u>The defective red blood cells during sickle cell anemia appear like a crescent moon and become sticky and rigid.</u> These defective cells cannot pass the blood vessels and get stuck in between. It may lead to a stoppage and slow down of blood flow, which in turn also obstructs the passage of oxygen throughout the body.
<u>The gene mutation is the cause of the anemia. This gene is responsible for the production of </u><u>haemoglobin</u><u>.</u> Haemoglobin is an iron-rich compound which provides the blood with its red color. The red blood cells carry oxygen with the help of hemoglobin, which binds oxygen. Abnormal hemoglobin is produced during sickle cell anemia, which makes the red blood cells rigid and sticky.
<u>These defective genes are passed from parents to the offspring and generate an inheritance pattern, which is called autosomal recessive inheritance</u>. This means both the parents must transfer the defective allele to produce an affected child.<u> If a person inherits a sickle cell gene from only one parent, he/she is a carrier of the disease.</u> This implies that the person can further pass on the gene to his/her progeny.
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Answer Details:
Grade: High School
Chapter: Sickle Cell Anaemia
Subject: Biology
Keywords:
Anemia, sickle cell anemia, red blood cells, oxygen, hemoglobin, blood vessels, mutation, inheritance pattern, autosomal recessive, iron-rich compound, blood, allele, gene.