Question

Explain how nondisjunction can lead to aneuploidies

Answer 1

Nondisjunction occurs when chromatids do not separate.

Aneuplodies have irregular numbers of chromosomes.

An aneuplody can occur as the result of a nondisjunciton.

Answer 2

In nondisjunction, if members of a pair of homologous chromosomes do not move apart during meiosis I or sister chromatids fail to separate during meiosis II, this means one gamete receives 2 of the same kind of chromosome and if either one of these abnormal gametes unites with a normal one at fertilization, the zygote will also have an abnormal number of particular chromosomes; which is known as an aneuploidy.