Constantinople was surrounded on all sides by a defensive wall and was well supplied, making it resistant to sieges. The Ottomans were only able to capture the city due to one of the city gates being left slightly ajar, allowing them to quickly bypass the wall and overrun the defenders.
Your answer is A, Conflict with Native Americans ended.
Louisiana purchase entailed negative consequences for most of the Louisiana population - blacks and Indians - and became one of the causes of acute social contradictions in modern America. In just 30 years, Americans ousted Indians from most of the Mississippi Valley, physically destroying or expelling them from their ancestral lands through fraudulent treaties
Native Americans and Kentucky pioneers
The Age Of Enlightenment, occurring in the 18th century, was a movement of intellectual and philosophical reasoning. in which people began to question the authority of the monarchy and the church. From this movement came the separation of church and state