Which mutation would most likely lead to cancer? a. a histone involved in DNA compaction that cannot bind DNA b. a growth factor
receptor that cannot dimerize c. a ribosomal protein that cannot participate in protein synthesis d. a voltage-gated ion channel that is always open and inhibits electrical signaling e. a receptor that can activate in the absence of ligand
One of the reasons of cancer is th transformation of the DNA inside the cell. The DNA inside a cell is bundled into an enormous number of individual qualities, every one of which contains a lot of directions advising the cell what capacities to perform, and its formation and separation.
The most usually changed quality in individuals with malignancy is p53 or TP53. Over half of malignant growths include an absent or harmed p53 quality. Most p53 quality transformations are procured. Germline p53 transformations are uncommon, however patients who convey them are at a higher danger of creating a wide range of sorts of malignant growth.
In malignant growth cells, the ErbB2 receptor tyrosine kinase can be actuated in two different ways, out of which one includes the enactment without ligand.
