Heart failure (HF) with reduced ejection fraction <em>is responsible for approximately 50% of cases of heart failure in the U.S. and it is associated with considerable morbidity and decreased quality of life.
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<u><em>Diagnostic code ICD-10-CM 2019 I50.2 Systolic (congestive) heart failure</em></u>, applicable to Heart failure with reduced ejection fraction [HFrEF].
Increasing extracellular K+ increases the positive charge outside the cell, making the inside of the cell (membrane potential) more negative. This inhibits net diffusion of Na+ into or out of the cell.
