Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
That is true.
Hoped I helped!
Venus is often called the sister planet of Earth because of its size, mass, and what its material its made of.
Answer:
I think the answer for your question is the letter c
Answer:
<h2>(14+16)/1000 *100= 3</h2>
Explanation:
Parental combinations are always more common then other recombinant progenies.
A female fly is heterozygous for three X-linked genes crossed with an abc/Y male. . If single crossover occurs between a & b and between b & c, then the double cross is that, which occurs in both.
Double cross over progeny are always least in number, so here double cross occurs are in abC 14 and ABc 16.
So we are expecting that number of double cross over progeny= (14+16)/1000 *100= 3
