Answer:
Sickle cell disease in an autosomal recessive inherited disease which is caused by the mutation in the HBB (hemoglobin-β gene) gene present on the chromosome no. 11. In sickle cell, the red blood cells become sickle shape due to the abnormal shape of hemoglobin present in it.
These sickle cells are known to form a blockage in the blood vessels thereby causing damage to the vital organs. Human spleen constantly destroys sickle cells because they get trapped in it which causes a disease called sickle cell anemia.
Sickle cell anemia is normally the problem in genetic disease which is inherited from the parents to children. When both the DNA strand has a mutation in their HBB gene then only this disease will affect the individual.
Biogeographic isolation refers to the separation of the members of the similar species, or a group of organisms, which breed and generate offspring that can further give rise to young ones.
The separation can be achieved by the geographical forces like oceans, rivers, and mountains, and by the biological forces, like hunting times, and spring or fall mating.
The full form of ATP is ANANTAPUR Indian Railway Station ATP
Ambient Temperature Pressure Chemistry ATP
All Trace Particles Chemistry ATP
Adenosine Tri-phosphate. But there are alot more :)
B. Increased exposure to UV light increases the risk of mutation occurring.