DNA replication initiates at specific points, called origins, where the DNA double helix is unwound. A short segment of RNA, called a primer, is then synthesized and acts as a starting point for new DNA synthesis. An enzyme called DNA polymerase next begins replicating the DNA by matching bases to the original strand.
Prophase 1 of meiosis <span>relative to the number of chromosomes of a given species, accounts for a significant amount of genetic variation in gametes.</span>