Nucleotides are the building blocks of nucleic acids. In DNA, there are four types of nucleotides each containing one of four nitrogenous bases: guanine (G), cytosine (C), adenine (A), thymine (T).
- The monomer exhibited in the figure is a NUCLEOTIDE, i.e., a purine (Adenine) nucleotide.
- A nucleotide is a molecule composed of a nitrogenous base, a pentose sugar (deoxyribose in DNA) and a phosphate group.
- Purine bases consist of a double‐ring structure having four nitrogen (N) atoms and five carbons (C) atoms.
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In eukaryotes, the DNA strands are linear, and DNA polymerase can't replicate the very ends of the DNA strands! These ends are "protected" by repeated sequences called "telomeres." Either the chromosome gets shorter with each replication, or else a special enzyme-nucleic acid complex called telomerase adds new telomeres to the ends. A prokaryotic chromosome is circular and thus does not have the problem of having ended.
<span>Eukaryotic DNA is wound around histones, coiled, and supercoiled -- to replicate it, there have to be unwinding mechanisms, and mechanisms to reduce the degree of coiling. In prokaryotes, the winding problem is much less, and there aren't any histones.</span>
Enzymes are sometimes called biological catalysts
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With chromosomes crossing over frequently, it's more likely that genetic defects will occur in offsprinfg.