The purpose was to amend the Articles of Confederation.
The Three-Fifths Compromise determined that 3 out of 5 slaves would be counted as people, giving the South an advantage in Congress
Native Americans had no immunity to European illnesses and their population was devastated by the (sometimes deliberate) introduction of diseases like smallpox. Over time, most surviving tribes were forcibly relocated from their traditional lands to make way for expanding European settlements.
So no
BUTT HOLE BE ITCHING AND BURNING