Variation in the relative frequency of different genotypes in a small population, owing to the chance disappearance of particular genes as individuals die or do not reproduce.
Genetic drift is a mechanism of evolution in which allele frequencies of a population change over generations due to chance (sampling error).
Genetic drift occurs in all populations of non-infinite size, but its effects are strongest in small populations.
Genetic drift can have major effects when a population is sharply reduced in size by a natural disaster (bottleneck effect) or when a small group splits off from the main population to found a colony (founder effect).