Louisville is the largest city in Kentucky, USA.
In general, slavery in the deep South was more brutal and inhumane than slavery in the Chespeake region, and the crops being harvested were more lucrative for the farmers. During this time period slavery was divided many into the South, which cause divisions with the North leading up to the Civil War.
Astronomers wanted to name the planet a name so with uranuas they named it after the "Greek god of the sky" and neptune was "the god of the sea."