Question

One of the genes affected in Diamond-Blackfan Anemia is called RPS19. This gene plays a role in maturation of the 40S subunit. Your sister tells you she heard that protein synthesis can occur normally if the large ribosomal subunit is present, even if the small subunit is not, because the large subunit is the part that decodes the information. You tell her that this is _____ .

Answer 1

Answer:

You tell her that this is incorrect.

Explanation:

The given information is incorrect as both small and large ribosomal subunits are required for protein synthesis. The eukaryotic ribosomes have E, P, and A sites. The A and P sites bind to the aminoacyl tRNA that carry the amino acid encoded by the codon of the mRNA.

The formation of peptide bond occurs between the amino group of amino acid in A site and the carboxyl group of amino acid present on P site. Both 40S and 60S subunit of ribosome contribute the A and P sites.