How does alternative rna splicing affect gene expression?

1 answer:

6 0

RNA splicing was first discovered in 1970s in viruses and subsequently in eukaryotes. Not long after, scientists discovered alternative patterns of pre-mRNA splicing that produced different mature mRNAs containing various combinations of exons from a single precursor mRNA. The first example of alternative splicing of a cellular gene in eukaryotes was identified in the IgM gene, a member of the immunoglobulin superfamily. Alternative splicing (AS) therefore is a process by which exons or portions of exons or noncoding regions within a pre-mRNA transcript are differentially joined or skipped, resulting in multiple protein isoforms being encoded by a single gene. This mechanism increases the informational diversity and functional capacity of a gene during post-transcriptional processing and provides an opportunity for gene regulation

You might be interested in

What letter represents a trench? a. A b. B c. C d. D e. E

viktelen [127]

The answer is b because there are cracks in the ocean that are caused by two plates crashing

7 0

2 years ago

Cuales son los componentes de la biogeografía?

aliya0001 [1]

Estos pueden ser desde una tipología de rocas, un habitat natural, comunidades urbanas y rurales, cuerpos de agua y afuentes, elementos morfológicos(volcanes, sierras, montañas), coberturas vegeatles. Existe una gran diversidad y abundancia de organismos que habitan en nuestro planeta.

3 0

3 years ago

How would the DNA in an eye cell and a heart cell compare?

ankoles [38]

Answer:

Almost all of the cells in your body share the same DNA as was found in that first cell. Eyes and heart are so different because different set of problems are made in the various eyes and heart cell

Explanation:

4 0

3 years ago

Which major processes were needed for the origin of life on Earth?

Romashka [77]

Answer:

Organic molecules produced from spontaneous synthesis or from meteorites

Explanation:

6 0

2 years ago

On a backpacking trip, Kenny hikes all day at a steady pace, covering 30 kilometers and burning 4000 Calories. At the school tra

emmasim [6.3K]

Answer:

A. If the aerobic pathway—cellular respiration—cannot meet the energy demand, then the anaerobic pathway—lactic acid fermentation—starts up, resulting in lactic acid buildup and "oxygen debt."

D. The rate of energy demand determines how the muscles will obtain energy, either from cellular respiration or from lactic acid fermentation if not enough oxygen is present.

Explanation:

It is important to consider that Kenny hikes all day but at a steady pace, whereas Janelle runs very fast. So Kenny's case, the supply of oxygen is sufficient to maintain aerobic respiration within the muscle cells. During this process only CO2, Water, and ATP are produced; therefore, there is no oxygen debt. We should keep in mind that the body shifts to anaerobic metabolism only when the supply of oxygen is limited.

In Janelle's case, running fast would need energy at higher rates and the supply of oxygen would not be sufficient to generate a high amount of ATPs. Therefore, to compensate for this deficiency, cells will start fermenting glucose to lactic acid and produce ATP and maintain energy demands. This lactic acid causes fatigue and this is why Janelle has aching and breathing hard. Breathing hard is also automatic reflux to inhale more oxygen and meet oxygen demands but even breathing hard would not be able to make it and the body will shift to anaerobic respiration automatically.

5 0

3 years ago