You are a geneticist and two very angry hobbits, Pippin and Lola, come storming into your office. Pippin and Lola have just had
a newborn baby girl named Beatrice. Beatrice has blue eyes, but pippin and Lola both have green eyes. Green eyes are dominant over blue eyes. Pippin thinks that Beatrice is not his baby, and is very angry with lola. Determine how it is in fact possible for Beatrice to be pippins baby girl.
A) What are pippin and Lola's genotype?
B) What is Beatrice's genotype?
A) What are pippin and Lola's genotype?
B) What is Beatrice's genotype?
2 answers:
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Answer : The dissociation constant of the PFK‑inhibitor complex is, 5 µM
Explanation :
The expression for reversible competitive inhibition when apparent Km affected by addition of the inhibitor is:
where,
= apparent value = 52 µM
= Michaelis–Menten constant = 40 µM
I = inhibitor concentration = 1.5 µM
= dissociation constant of the PFK‑inhibitor complex
Now put all the given values in the above formula, we get:
Therefore, the dissociation constant of the PFK‑inhibitor complex is, 5 µM