Answer:
Reproductive System
All the body systems have one role or the other to play in digestion and absorption. Even the excretory system removes waste and toxins from the body, leaving the useful materials.
However, the reproductive system is not actively involved in digestion.
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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<span>Proteins make DNA which then creates RNA.</span>
Hey there!
Number 3, "has more people than ever before" is correct. As there are more people, there is a greater need more resources.
Hope this helped, have a good night!
Answer:
C) 30,000
Explanation:
According to the given information, the bacterial mRNA consists of about 800 nucleotides. Three consecutive nucleotides together make one genetic codon which in turn codes for one specific amino acid in the protein encoded by this mRNA.
So, an mRNA with 800 nucleotides will have total 800/3 = 266.67 or 266 genetic codes. The protein encoded by this mRNA would have a total of 266 amino acids.
Given that one amino acid imparts 110 units to the molecular weight of the protein, the protein with 266 amino acids have the molecular weight= 266 x 110 = 29260, that is about 30,000.
