The answer to this question would be "B"
Venice and Florence emerged as key centers of trade in the Mediterranean, based on the trade of silk, cotton, wool and spices. The Italian city-states were the bridge between the Byzantine Empire, Western Europe, North Africa and the Middle East.
Im not sure if this is correct but I think that the great Majority left Europe to worship God....
<span>It completed the expansion of the US to the Pacific</span>