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lozanna [386]
3 years ago
6

Diseases caused by single-gene defects, such as cystic fibrosis, hemophilia, muscular

Biology
1 answer:
frosja888 [35]3 years ago
6 0

Answer:

Gene therapy

Explanation:

Gene therapy can be defined as the methodologies used to modify/restore the expression of target genes and thus cure and treat genetic disorders. Gene therapy approaches consist of delivering specific nucleic acids (either RNA or DNA) in the cells of the individual to be treated. Some of the most important gene therapy approaches include the use of small interfering RNAs (siRNAs) in order to block target gene expression, adenovirus vectors to insert genes into host cells, the use of the CRISPR-Cas9 genome editing system to insert specific sequences by the mechanism of homologous recombination, etc.

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The elephants represented in lanes 3 and 5 could have been a match to the ivory sample if you failed to amplify one allele in ei
olga_2 [115]

About the question:

I failed to find the result of the PCR / electrophoresis. However, I will try to explain when to still consider a sample, and when to exclude it.

Answer:

Probably elephants 1, 2, 4, and 6 exposed a pattern of lines that differed in most alleles from the ivory´s pattern. So they were considered to be different and, hence, excluded. However, elephants 3 and 5 only were different in one allele, which might be due to the amplification failure. In these last situations, the experiment must be run again, and include many markers.

Explanation:

The genetic profile is the series of alleles, characteristic of each individual, concerning a series of DNA fragments.

Once genetic profiles are obtained by using PCR/electrophoresis, they must be subjected to interpretation. The researcher must compare profiles to find concordance between individuals or the lack of it.

In the exposed example, probably we have a profile of the ivory sample, and we need to find out to what individual or population it belongs to. So we need to compare the pattern of bands of the different lanes with the ivory´s pattern of bands.

In resumed terms, if the ivory´s patterns completely match with another lane pattern, then this is the individuals or population to whom it belongs the ivory. However, if they do not match, we need to exclude this individual.

But this is not as easy as it looks like. Sometimes it is difficult to interpret the results because bands are not so clear, and sometimes there are failures during amplification, as said before in the statement of the problem.

In these situations, what you need to do is look for the lanes that match the most with the ivory one and discard those that differ the most. These last patterns probably belong to a different animal or population, that why they can be excluded. Individuals suspected of being the same as the individual understudy or belonging to the same population, must be subducted to a repetition of the study. Also, the use of several markers in the study increases the matches chances.

So, in the exposed example, if the amplification fails in one allele, elephants 3 and 5 could be a match to the ivory sample, probably because all the other alleles do match. You can only exclude them if, after the experiment repetition, the involved allele is still different. On the other hand, you can eliminate the elephants 1, 2, 4, and 6 because their pattern bands are significantly different from the ivory´s patterns, so you do not even need to repeat the experiment.

7 0
2 years ago
What does archaeocetes literally mean ?
anygoal [31]

Answer:

ancient whales

Explanation:

3 0
3 years ago
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Why do you think a small surface area to volume ratio would cause a problem?
Scilla [17]

Answer:

The important point is that the surface area to the volume ratio gets smaller as the cell gets larger.

5 0
3 years ago
The ears and stomach help the body fight
olga nikolaevna [1]

Answer:

It going to be your gut that helps the ears and stomach fight the body

Explanation:  

<em>#CarryOnLearning</em>

<em>#StaySafe</em>

5 0
3 years ago
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Ehrlich and Raven hypothesized that if a new defensive trait evolves in a single plant species (or if a new trait to counteract
Blababa [14]

Answer:

Coevolution

Explanation:

Ehrlich and Raven observed butterfly species and their host plants. Plant species had adopted a series of defence mechanisms against butterflies. In response the butterflies also evolved new traits to avoid these defence mechanisms.

In this way both butterflies and plants influenced each other's traits and they co evolved. The coevolution can lead to accumulation of lot of different characteristics which can lead to formation of new species and species diversification. Formation of new species will be observed both in plants and butterflies.

7 0
3 years ago
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