Answer and Explanation:
The mechanism of action of statins begins with the inhibition of a protein called HMG-CoA reductase, allowing its substrate to accumulate in the body and promote cholesterol reduction. At that moment, a transporter called OATP (Organic Anion Transporting Polypeptides) takes statins to the epatic tissue where they will be transformed and metabolized until they are eliminated through bile. This elimination is influenced by the P-glycoprotein, which is the main cause of the efflix presented by the bili. This process can get help from other molecules like some protease inhibitors, digoxin and cyclosporine.
There would be more hours of sunlight at the equator
Answer: Anything living needs to have certain conditions, if for example a group of flightless birds who are adapted for warm weather had their environment get colder each year and more extreme the surrounding plants and other animals may have a difficult time surviving and this will cause the birds to have less food. The birds also will not be accustomed to these changes and will not be able to adapt their bodies fast enough. This also makes reproduction difficult and in turn further dwindles the population.
Hope this helps!
Explanation:
The immune system is the bodies defense against invaders and is located in all body tissues with concentration in the mucosal surfaces and skin.
I think the answer to this is E